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  • 9 VIDEOS
  • VSL#3® Probiotics for Digestive Health, IBS & UC Symptoms - 112.5B CFUs, High-Potency, Multi-Strain, Live, Refrigerated Probiotic, Medical Food for Gut Health Support in Men & Women, 60 Capsules
  • Finding the right strains for your desired health benefitsVSL#3

VSL#3® Probiotics for Digestive Health, IBS & UC Symptoms - 112.5B CFUs, High-Potency, Multi-Strain, Live, Refrigerated Probiotic, Medical Food for Gut Health Support in Men & Women, 60 Capsules

4.6 out of 5 stars (3,161)
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Size: 60 Count (Pack of 1)

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Brand Name VSL #3
Primary Supplement Type Probiotic
Item Form Capsule
Diet Type Gluten Free, Halal, Kosher, Vegan
Product Benefits Dietary management of irritable bowel syndrome (IBS) and ulcerative colitis (UC), Digestive health support, Gut health support
Age Range Description Adult
Container Type Bottle
Dosage Form Capsule
Manufacturer VSL#3
Manufacturer Part Number Cap-Parent
Best Sellers Rank
ASIN B07WX1LVHL
Customer Reviews
4.6 out of 5 stars (3,161)

4.6 out of 5 stars
Unit Count 60 Count
Item Weight 4.8 ounces
Item Dimensions 4.33 x 4.72 x 4.72 inches
Number of Items 1
Total Servings Per Container 30

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VSL#3® Probiotics for Digestive Health, IBS & UC Symptoms - 112.5B CFUs, High-Potency, Multi-Strain, Live, Refrigerated Probiotic, Medical Food for Gut Health Support in Men & Women, 60 Capsules

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This item: VSL#3® Probiotics for Digestive Health, IBS & UC Symptoms - 112.5B CFUs, High-Potency, Multi-Strain, Live, Refrigerated Probiotic, Medical Food for Gut Health Support in Men & Women, 60 Capsules
$74.95 ($1.25/count)
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IBgard Gut Health Supplement, Peppermint Oil Capsules for Abdominal Comfort, 48 Capsules
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Important information

Safety Information

VSL#3® is intended for use under medical supervision.

Ingredients

Strains: Streptococcus thermophilus, Bifidobacterium breve, Bifidobacterium lactis (previously classified as B. longum), Bifidobacterium lactis (previously classified as B. infantis), Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus helveticus (previously classified as L. delbrueckii subsp. bulgaricus) Other Ingredients: Vegetal capsule (hydroxypropyl methylcellulose), cornstarch, magnesium stearate, silicon dioxide, stearic acid, microcrystalline cellulose

Directions

Typical adult dosage is 1–2 capsules up to 4 times daily, or as directed by a physician. Avoid consuming with hot foods or drinks, as heat may reduce probiotic viability. Consistent daily use for several weeks may be needed to help support microbiota balance.

Legal Disclaimer

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Amazon.com assumes no liability for inaccuracies or misstatements about products.

Product description

VSL3 Capsules
VSL3 Capsules
VSL3 Capsules
VSL3 Capsules
VSL3 Capsules
VSL3 Capsules

Find the Product That's Right For You

VSL#3 Probiotics Capsules

VSL#3 Probiotic Powder

VSL4 Gut Daily Probiotics

VSL4 Vaginal Health

Customer Reviews
4.6 out of 5 stars 3,161
4.7 out of 5 stars 328
4.5 out of 5 stars 319
4.4 out of 5 stars 46
Supports
Gut Health in Both Women & Men Gut Health Support Men & Women Digestive Health & Gut Health Vaginal Microbiota Balance
Unit Count
60 Capsules 30 Packets 30 Capsules 30 Capsules
Storage Requirement
Refrigerated Refrigerated Shelf-stable Shelf-stable
Potency Level
112.5 Billion CFU per capsule 450 Billion CFU per packet 30 Billion CFU per capsule 10 Billion CFU per capsule
Days Supply
60 30 30 30

From the brand

  2. VSL3 Powder
  3. VSL3 Capsules
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  5. VSL3 Powder
  6. cold shipped
  7. legacy
  8. VSL #3® Probiotics for Digestive Health, IBS & UC Symptoms - 112.5B CFUs, High-Potency, Multi-Str...
    VSL #3® Probiotics for Digestive Health, IBS & UC Symptoms - 112.5B CFUs, High-Potency, Multi-Str...
    VSL #3® Probiotics for Digestive Health, IBS & UC Symptoms - 112.5B CFUs, High-Potency, Multi-Str...
    VSL #3® Probiotics for Digestive Health, IBS & UC Symptoms - 112.5B CFUs, High-Potency, Multi-Str...

    Shop VSL3 Capsules

Product details

  • Product Dimensions ‏ : ‎ 4.33 x 4.72 x 4.72 inches; 4.8 ounces
  • Date First Available ‏ : ‎ August 21, 2019
  • Manufacturer ‏ : ‎ VSL#3
  • ASIN ‏ : ‎ B07WX1LVHL
  • Best Sellers Rank: #9,312 in Health & Household (See Top 100 in Health & Household)
  • Customer Reviews:
    4.6 out of 5 stars (3,161)

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Customer reviews

4.6 out of 5 stars
3,161 global ratings

Customers say

Customers find this probiotic effective for digestive health, particularly for IBS-C and GERD symptoms, and one customer mentions it works wonders for IBS-D. The product receives positive feedback for its quality, with one customer noting it's recommended by a professional gastroenterologist. Customers disagree on whether the product is worth the price, and there are mixed opinions about temperature control, with some saying it must be kept cold while others note it's okay at room temperature. Customers disagree on the product's durability, with some receiving it in good condition while others report seal damage.
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168 customers mention quality, 163 positive, 5 negative
Customers find these probiotics to be of high quality, with one customer noting they are recommended by their Low Oxalate group.
...I now have it again and honestly it’s a great product. It does have to be refrigerated and the box is a refrigerated packing.. so impressive. Try it !Read more
Glad you are carrying this product again. It’s the best probiotic at the best price point on the market and packaging and delivery excellent.Read more
Good product that Amazon delivers successfully. It comes in an insulation-lined cardboard box with a cool packet.Read more
these are the best probiotics! And they came in a package with ice packs to stay cold. The only thing that helps my UC.Read more
157 customers mention effectiveness, 138 positive, 19 negative
Customers report that the probiotic supplement works extremely well, particularly for digestive health and stomach issues, with one customer noting its effectiveness in controlling bowel movements.
This is a live probiotic, it is very effective, and improves digestion and elimination. I am a repeat consumer and am very satisfied.Read more
I have used this product for the last 10+ years, works great!...Read more
Great product just wish it wasn’t so pricey. Works well and doctor recommended. That’s why I pay the price.Read more
This was recommended by my dietitian as I have IBSD. It works very well. Comes in dry ice and should be kept in your refrigerator.Read more
142 customers mention digestive health, 119 positive, 23 negative
Customers report positive effects on digestive health, with the probiotics helping with gut issues, IBS-C and GERD symptoms, and regulating bowel movements. One customer specifically mentions relief from moderate to severe bloating and gas.
Great for IBSRead more
Improved IBS symptoms and gut healthRead more
The ONLY product that helps my IBSRead more
...Since I have started these I have had regular bowel movements with no pain....Read more
107 customers mention value for money, 39 positive, 68 negative
Customers have mixed opinions about the probiotic supplement's value, with some finding it worth the price while others consider it a waste of money.
...This product is pricey, but it really helps, I found that taking 2 capsules every other day before dinner works best for me, and my attacks have...Read more
...I still take it daily, 10 years later. It’s pricy but worth it. Sure you can find something cheaper but make sure to compare the dosage breakdown....Read more
Expensive but well worth it, my gastroenterologist recommends this and it’s the best probiotic on the market, especially if you have gastric...Read more
Very expensive. Took one. Could not use. Bad side effect. Not returnable. Wasted $72 plus shipping.Read more
37 customers mention temperature, 19 positive, 18 negative
Customers have mixed experiences with the temperature of the probiotic supplement: while some find it acceptable at room temperature, others report that it arrives hot instead of cold.
Delivery was fast. I’m glad the product was kept cold. Very well pleased.Read more
...it (despite the fact that it came in a styrofoam cooler) the product was warm, had been on a UPS truck for at least a full day, and now I am stuck...Read more
I love how it was shipped carefully and professionally to keep it cold. VSL#3 contains the best probiotics I've ever taken....Read more
The medication is supposed to to be kept refrigerated. It arrived hot not cold.Read more
33 customers mention refrigeration, 15 positive, 18 negative
Customers have mixed opinions about the refrigeration requirements of the probiotic supplement, with some appreciating that it stays refrigerated, while others note that it needs to be kept cold.
...The most difficult thing for me is that it needs to be refrigerated and I forget to take it before bedtime because I don’t go in the kitchen....Read more
This probiotic requires refrigeration, but the seller is using the wrong shipping method....Read more
Great product, Must be refrigerated. Comes packed with a cold pack. Check mail every day till it arrives.Read more
...Work well - can tell when a dose is missed. Shipt cold and kept refrigerated.Read more
13 customers mention durability, 7 positive, 6 negative
Customers have mixed experiences with the probiotic's durability, with some reporting the product arrives in good condition while others mention receiving bottles with broken seals.
It came in before due date.,In good condition. very pleased.Read more
...Came to me with safety seal clearly broken. Tried to return through Amazon- said I must call manufacturer. Left a message with them, last week....Read more
...good news is that I only need to take one a day, so the bottle lasts two months. The delivery was fast, and the packing was superb....Read more
After using this product for a couple of weeks I’m in worse shape then before. A tremendous amount of intestinal pain and constipation....Read more
Comes in super packing!
5 out of 5 stars
Comes in super packing!
This product works great. When they ship it - comes in a box with ice packs (you can reuse) and it’s recyclable! Stays cold even if it’s 100 degrees out.
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Top reviews from the United States

  • Debbie McFarlane
    5 out of 5 stars
    Pricey but a great product
    Reviewed in the United States on April 14, 2026
    Size: 60 Count (Pack of 1)
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    It’s expensive but still a great product. When my stomach is upset after a meal or it wakes me up in the middle of the night, I take 2-3 probiotics and within 15 minutes, I feel better. It also helps to prevent reflux. If I eat supper too close to bedtime which is often as I work sometimes 10 hours a day, I take 2 of the probiotics and don’t have to worry about reflux waking me or if I do have a case, it’s mild.

    3 people found this helpful
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  • Margaret B. Moss
    5 out of 5 stars
    Game changer for GI problems
    Reviewed in the United States on June 2, 2026
    Size: 60 Count (Pack of 2)
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    I started having serious "GI" problems two years ago. I was diagnosed with lymphocytic colitis — an uncommon, incurable condition, which can make life miserable. VSL#3 is the only probiotic I saw mentioned in clinical articles about the condition. My own experience is that it works wonders. I still have a restricted diet and take medication, but through my own trial and error, VSL#3 makes a huge difference.

    One person found this helpful
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  • Patricia Justice
    5 out of 5 stars
    Great probiotic for sons IBD UC
    Reviewed in the United States on May 30, 2026
    Size: 60 Count (Pack of 2)
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    My son has IBD UC and this has helped him reduce the side-effects from this disease

    One person found this helpful
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  • CoryJamaul
    5 out of 5 stars
    Helps with Autism-linked IBS
    Reviewed in the United States on May 18, 2026
    Size: 60 Count (Pack of 1)
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    I have autism-linked IBS and have suffered with digestive dysfunction for much of my life. It has gotten worse with age, so I've become more active with trying things to improve my gut health. This product, along with with Saccharomyces boulardii, have had a tremendous positive impact!

    I took two capsules a day for a month, and the pain, discomfort, bad bowel movements, bloating, and gassiness all subsided. My quality of life actually improved by a very noticeable amount. I'll be continuing the treatment for a second and possibly third month!

    2 people found this helpful
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  • Harry Feinberg
    5 out of 5 stars
    Great product
    Reviewed in the United States on May 26, 2026
    Size: 60 Count (Pack of 4)
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    Great product

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  • Shep
    4 out of 5 stars
    Not Sure
    Reviewed in the United States on January 28, 2026
    Size: 60 Count (Pack of 1)
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    Seems to work somewhat where other probiotics didn’t work at all as well as upsetting my stomach. I will wait and see and perhaps reorder to give my system time to adjust.

    2 people found this helpful
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  • Carmen L.
    5 out of 5 stars
    Only thing that really worked
    Reviewed in the United States on December 1, 2025
    Size: 60 Count (Pack of 1)
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    I am a Zepbound user for about 6 months. I’m also a person with diverticulosis for over 5 years. Add to this, I recently had a knee replacement with tons of meds for pain. All of this has wreaked havoc on my digestive system. Post surgery I didn’t go potty for 6 days and finally gave myself a suppository, but even that wasn’t the most helpful. You name it, I’ve tried it. Then I remembered about 10-12 years ago, a naturopath prescribed VSL#3 for my then IBS, so out of total desperation, I ordered it. Without getting too graphic prior to VSL#3, I had bowel movements maybe once every 2-3 days and every time I ate, I was miserable. I felt exhausted and sluggish all the time. After taking 2 pills at bedtime I woke up the next morning and within an hour, I had a bowel movement Dr Oz would be proud of. I had energy, focus and all the cramps and bloating feeling completely disappeared. The most difficult thing for me is that it needs to be refrigerated and I forget to take it before bedtime because I don’t go in the kitchen. (Note: I prefer taking it at night so I can go in the morning before I start my day. I’m nervous to take it in the morning and have to rush to find a bathroom when I’m on the golf course on someplace that isn’t convenient).

    I’ve tried so many probiotics, and was even told to take MiraLAX or Hayley’s MO by doctors up to 2 times a day, Metamucil, BioGard, and so many others…. Nothing works like this! Yes it’s expensive. Yes it’s inconvenient to have to put it in the fridge. It works! It works during the night. It works every day. It’s worth every freaking penny! I feel great!

    46 people found this helpful
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  • Laiz
    5 out of 5 stars
    The best
    Reviewed in the United States on February 2, 2026
    Size: 60 Count (Pack of 1)
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    One of the best probiotics I’ve used. I’m gluten and lactose intolerant and often experience bloating, and this has helped noticeably with digestive comfort. It feels effective without being harsh, and I saw results quickly.

    The only downside is the price, I wish it were more affordable. Still, it works very well and I’d recommend it for anyone with sensitive digestion.

    13 people found this helpful
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Product Summary: VSL#3® Probiotics for Digestive Health, IBS & UC Symptoms - 112.5B CFUs, High-Potency, Multi-Strain, Live, Refrigerated Probiotic, Medical Food for Gut Health Support in Men & Women, 60 Capsules

From VSL #3

4.6 out of 5 stars, 3,161 ratings

Customer reviews

300+ bought in past week

Price

No featured offers available

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About this Item

  • #1 GASTROENTEROLOGIST-RECOMMENDED: Trusted by experts, VSL#3 stands out as the #1 gastroenterologist-recommended multi-strain probiotics brand, and is designed for gut health in both women and men.
  • HIGH-POTENCY RELIEF: Each capsule of VSL#3 delivers 112.5 billion CFU of live probiotics, significantly more than most other leading brands. Now available as a 4 pack.
  • EIGHT-STRAIN BENEFITS: Scientifically formulated with 8 complementary probiotic strains from 3 different genera, VSL#3 is designed to restore balance and support issues like bloating and irregularity associated with serious gut conditions.
  • LIVE & REFRIGERATED FOR MAXIMUM POTENCY: Unlike many shelf-stable probiotics, VSL#3 probiotics are carefully stored and shipped under refrigerated conditions to ensure maximum potency, so you get the full benefits of every dose.
VSL#3 also provides flexibility since it maintains effectiveness when kept at room temperature for up to 2 weeks.
  • DAIRY-FREE, ALLERGEN-FREE & MORE: Dairy is a common trigger food for people with digestive issues – so unlike many other probiotic brands, VSL#3 has none. VSL#3 is also gluten-free, non-GMO, nut-free, vegan, kosher, and halal-certified. Perfect for daily use, each bottle contains 60 capsules to support your journey toward digestive relief and optimal gut health.
  • SUSTAINABLY PACKAGED: Ships in temperature-controlled packaging with a 100% curbside recyclable insulated thermal lining.

Product Description

VSL#3 IS THE #1 GASTROENTEROLOGIST-RECOMMENDED MULTI-STRAIN PROBIOTICS BRAND. VSL#3 capsules are scientifically formulated for the dietary management of irritable bowel syndrome (IBS) and ulcerative colitis (UC). VSL#3 capsules contain eight complementary strains from three different genera are high-potency (112.5B CFU per capsule), and are refrigerated for maximium viability. VSL#3 is dairy-free, soy-free, gluten-free, non-GMO, kosher & halal certified, nut-free and vegan. ProVoice surveys.

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Size

  • 60 Count (Pack of 1)
  • 60 Count (Pack of 2)
  • 60 Count (Pack of 3)
  • 60 Count (Pack of 4)
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Important Information

Safety Information

VSL#3® is intended for use under medical supervision.

Ingredients

Strains: Streptococcus thermophilus, Bifidobacterium breve, Bifidobacterium lactis (previously classified as B. longum), Bifidobacterium lactis (previously classified as B. infantis), Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus helveticus (previously classified as L. delbrueckii subsp. bulgaricus) Other Ingredients: Vegetal capsule (hydroxypropyl methylcellulose), cornstarch, magnesium stearate, silicon dioxide, stearic acid, microcrystalline cellulose

Directions

Typical adult dosage is 1–2 capsules up to 4 times daily, or as directed by a physician. Avoid consuming with hot foods or drinks, as heat may reduce probiotic viability. Consistent daily use for several weeks may be needed to help support microbiota balance.

Legal Disclaimer

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

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